金沢大学附属病院 病理診断科・病理部

研究・業績performance

論文

2021年度

  1. Significant Improvement After Surgery for a Symptomatic Osteoblastoma in a Patient with Camurati-Engelmann Disease:Case Report and Literature Review. Yonezawa H, Hayashi K, Yamamoto N, Takeuchi A, Tada K, Miwa S, Igarashi K, Kimura H, Aoki Y, Morinaga S, Araki Y, Asano Y, Sakurakichi K, Ikeda H, Nojima T, Tsuchiya H. Calcifies Tissue Int. 2021 Jun; 108 
  2. Notch-Hes1 signaling activation in Caroli disease and polycystic liver disease. Takahashi K, Sato Y, Yamamura M, Nakada S, Tamano Y, Sasaki M, Harada K. Pathol Int. 2021 Jun 24
  3. Diversity in cell differentiation, histology, phenotype and vasculature of mass-forming intrahepatic cholangiocarcinomas. Can H N, Takahashi K, Yamamura M, Li Z, Sato Y, Yoshimura K, Kozaka K, Tanaka M, Nakanuma Y, Harada K. 2021 May 21
  4. Durable response achieved using Pazopanib for germ tumor cells:A case report. Takezawa Y, Yaegashi H, Iijima M, Kawaguchi S, Nohara T, Shigehara K, Izumi K, Kadono Y, Ikeda H, Mizokami A. Mol Clin Oncol. 2021 Mar; 14
  5. The pronounced lung lesions developing in LATY136F knock-in mice mimic human IgG4-related lung disease. Waseda Y, Yamada K, Mizuguchi K, Ito K, Watanabe S, Zuka M, Ishizuka T, Malissen M, Malissen B, Kawano M, Matsui S. PLoS One. 2021 Mar 4; 16
  6. Diagnostic accuracies of intraoperative frozen section and permanent section examinations for histological grades during open biopsy of bone tumors. Miwa S, Yamamoto N, Hayashi K, Takeuchi A, Igarashi K, Tada K, Higuchi T, Yonezawa H, Morinaga S, Araki Y, Asano Y, Ikeda H, Nojima T, Tsuchiya H. 2021 Mar; 26
  7. A phase I study of preoperative(neoadjuvant) chemotherapy with gemcitabine plus nab-paclitaxel for resectable pancreatic cancer. Tajima H, Makino I, Gabata R, Okazaki M, Obatake Y, Shimbashi H, Nakamura S, Saito H, Shimada M, Yamaguchi T, Okamoto K, Moriyama H, Kinoshita J, Nakamura K, Miyashita T, Ninomiya I, Fushida S, Ikeda H, Ohta T. 2021 Feb; 14
  8. Mutiple Malignant Lymphomas of the Bile Duct Developing after Spontaneous Regression of an Autoimmune Pancreatits-like Mass. Ohtsubo K, Yamashita K, Yanagimura N, Suzuki C, Tanimoto A, Nishiyama A, Takeuchi S, Iwaki N, Kawano M, Izumozaki A, Inoue D, Gabata T, Ikeda H, Watanabe M, Yano S. 2021 Feb 1; 60
  9. Tertiary lymphoid tissue in early-stage IgG4-related tubulointerstitial nephritis incidentally detected with a tumor lesion of the ureteropelvic junction: a case report. Miyanaga T, Mizuguchi K, Hara S, Zoshima T, Inoue D, Nishioka R, Mizushima I, Ito K, Fujii H, Yamada K, Sato Y, Yanagita M, Kawano M. BMC Nephrol. 2021 Jan 19; 22
  10. Histiocytic sarcoma folliwing combination chemotherapy for primary mediastinal germ cell tumor: a diagnostic dilemma. Yaegashi H, Kato Y, Nohara T, Izumi K, Kadono Y, Miyagi T, Nakashima T, Yoshimura K, Sato Y, Harada K, Mizokami A. Int Cancer Conf J. 2021 Jan 9; 10
  11. Similar Recurrence Rate Between Gleason Score of Six at Positive Margin and Negative  Margin After Radical Prostatectomy. Kano H, Kadono Y, Kadomoto S, Iwamoto H, Yaegashi H, Iijima M, Kawaguchi S, Nohara T, Shigehara K, Izumi K, Ikeda H, Mizokami A. Anticancer Res. 2021 Jan; 41
  12. The number of osteoclasts in a biopsy specimen can predict the efficacy of neoadjuvant chemotherapy for primary osteosarcoma. Araki Y, Yamamoto N, Hayashi K, Takeuchi A, Miwa S, Igarashi K, Higuchi T, Abe K, Taniguchi Y, Yonezawa H, Morinaga S, Asano Y, Ikeda H, Nojima T, Tsuchiya H. Sci Rep. 2021 Jan 21; 11

2020年度

  1. Bronchoesophageal fistula formation after three courses of nivolumab for cinoma of unknown primary with a subgroup of lung squamous cell carcinoma. Nishiyama A, Sakaguchi H, Yanagimura N, Suzuki C, Otani S, Tanimoto A, Yamashita K, Takeuchi S, Ohtsubo K, Ikeda H, Yano S. Oof Med Case Reports. 2020 Dec; 28
  2. Low-grade myofibroblastic sarcoma of the levator scapulae muscle: a case report and literature review. Yonezawa H, Yamamoto N, Hayashi K, Takeuchi A, Miwa S, Igarashi K, Langit M, Kimura H, Shimozaki S, Kato T, Morinaga S, Araki Y, Asano Y, Ikeda H, Nojima T, Tsuchiya H. BMC Musculoskelet Disordering. 2020 Dec 10; 21
  3. Intraoperative ultrasonography-guided surgery for malignant soft tissue tumor. Takeuchi A, Yamamoto N, Hayashi K, Miwa S, Igarashi K, Yonezawa H, Morinaga S, Araki Y, Asano Y, Ikeda H, Tsuchiya H. J Sure Oncol. 2020 Dec; 122
  4. Accuracy of histological grades from intraoperative  frozen-section diagnoses of soft-tissue tumors.  Miwa S, Yamamoto N, Hayashi K, Takeuchi A, Igarashi K, Tada K, Higuchi T, Yonezawa H, Morinaga S, Araki Y, Asano Y, Ikeda H Nojima T, Tsuchiya H. Int J Clin Oncol. 2020 Dec; 25
  5. The relation between anti-TGBFR1 immunohistochemical reaction and low Ki67,small tumor size and high estrogen receptor expression in invasive breast cancer. Nakamura R, Oyama T, Inokuchi M, Ishikawa S, Hirata M, Kawashima H, Ikeda H, Dobashi Y, Ooi A. Pathol Int. 2020 Jun; 70
  6. Anti-tumor Activity of the Small Molecule Inhibitor PRI-724 Against β-Catenin-activated Hepatocellular Carcinoma. Gabata R, Harada K, Mizutani Y, Ouchi H, Yoshimura K, Sato Y, Kitao A, Kimura K, Kouji H, Miyashita T, Tajima H, Ohta T. Anticancer Res. 2020 Sep; 40
  7. Surgically resected praimary esophageal choriocarcinoma accompanied with Barrett’s adenocarcinoma:a case report. Fujiwara Y, Okamoto K, Ninomiya I, Saito H, Yamaguchi T, Terai S, Kinoshita J, Makino I, Nakamura K, Fushida S, Ikeda H, Ohta T. Surgery Case Rep. 2020 Sep29; 6
  8. ANCA-associated nephritis without crescent formation has atypical clinicopathological features: a multi center retrospective study. Zoshima T, Suzuki K, Suzuki F, Hara S, Mizuguchi K, Ito K, Mizushima I, Fujii H, Nomura H, Kawano M. Clinical and experimental nephrology. 2020 July;10
  9. Clinical features and diagnostic imaging of cholangiolocellular carcinoma compared with other primary liver cancers: a surgical perspective. Takamura H, Gabata R, Obatake Y, Nakanuma S, Hayashi H, Kozaka K, Sasaki M, Okazaki M, Yamaguchi T, Shimbashi H, Terai S, Okamoto K, Makino I, Kinoshita J, Nakamura K, Miyashita T, Tajima H, Ninomiya I, Fushida S, Kitao A, Kitahara M, Arai K, Tamashita T, Yamashita T, Ikeda H, Satoh Y, Harada K, Kaneko S, Gabata T, Kosaka T, Ohta T. Techno’s Cancer Res Treat. 2020 Jan-Dec; 19.
  10. Similar Recurrence Rate Between Gleason Score of Six at Positive Margin and Negative  Margin After Radical Prostatectomy. 
  11. 肝転移巣で混合腺神経内分泌癌が示唆された膵腫瘍の 1 例.下田翼 水口敬司 中田聡子 池田博子. 日本臨床細胞学会雑誌 第59巻5号

2019年度

  1. Two cases of primary supratentorial intracranial rhabdomyosarcoma with DICER1 mutation which may belong to a “spindle cell sarcoma with rhabdomyosarcoma-like feature, DICER1 mutant”. Sakaguchi M, Nakano Y, Honda-Kitahara M, Kinoshita M, Tanaka S, Oishi M, Noguchi K, Fukuda M, Maeba H, Watanabe T, Hayashi Y, Ikeda H, Minato H, Ichimura K, Nojima T, Nakada M. Brain Tumor Pathol. 2019 Oct;36(4):174-182.
  2. Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance. Kita K, Fukuda K, Takahashi H, Tanimoto A, Nishiyama A, Arai S, Takeuchi S, Yamashita K, Ohtsubo K, Otani S, Yanagimura N, Suzuki C, Ikeda H, Tamura M, Matsumoto I, Yano S.Cancer Sci. 2019 Oct;110(10):3215-3224.
  3. [A Case of Histiocytoid Breast Carcinoma Accompanied by Multiple Axillary Lymph Node Metastases]. Terakawa H, Gabata R, Ishikawa S, Hirata M, Inokuchi M, Kawashima H, Miyashita T, Tajima H, Takamura H, Ninomiya I, Fushida S, Ohta T, Oyama T, Ikeda H. Gan To Kagaku Ryoho. 2019 Jun;46(6):1049-1051.
  4. Solidified mucinous tumor of the ovary presenting characteristic MRI finding. Matsumoto J, Yoshida K, Inoue D, Yoneda N, Ikeda H, Mizumoto Y, Gabata T. Eur J Radiol Open. 2019 Jan 28;6:68-71.
  5. Detection of sentinel lymph node using contrast-enhanced agent, Sonazoid™, and evaluation of its metastasis with superb microvascular imaging in oral and oropharyngeal cancers: a preliminary clinical study. Wakisaka N, Endo K, Kitazawa T, Shimode Y, Kato K, Moriyama-Kita M, Koda W, Ikeda H, Ishikawa K, Ueno T, Nakanishi Y, Kondo S, Sugimoto H, Yoshimura K, Tsuji H, Kawashiri S, Omoto K, Yoshizaki T. Acta Otolaryngol. 2019 Jan;139(1):94-99.
  6. Amplicons in breast cancers analyzed by multiplex ligation-dependent probe amplification and fluorescence in situ hybridization. Ooi A, Inokuchi M, Horike SI, Kawashima H, Ishikawa S, Ikeda H, Nakamura R, Oyama T, Dobashi Y. Hum Pathol. 2019 Mar;85:33-43.
  7. The changes underwent by free fat pads used for pulmonary air leakage repair. Matsumoto I, Oda M, Ikeda H, Kimura K, Tamura M, Takemura H. Gen Thorac Cardiovasc Surg. 2019 Feb;67(2):266-269.
  8. The clinicopathological analysis of receptor tyrosine kinases in meningiomas: the expression of VEGFR-2 in meningioma was associated with a higher WHO grade and shorter progression-free survival. Nakada S, Sasagawa Y, Tachibana O, Iizuka H, Kurose N, Shioya A, Guo X, Yamada S, Nojima T. Brain Tumor Pathol. 2019 Jan;36(1):7-13.
  9. Characterization of the Inner and Outer Fiber Layers in the Developing Cerebral Cortex of Gyrencephalic Ferrets. Saito K, Mizuguchi K, Horiike T, Dinh Duong TA, Shinmyo Y, Kawasaki H. Cereb Cortex. 2019 Sep 13;29(10):4303-4311.
  10. Imaging and pathological features of gastric lesion of immunoglobulin G4-related disease: A case report and review of the recent literature. Inoue D, Yoneda N, Yoshida K, Nuka H, Kinoshita J, Fushida S, Toshima F, Minami T, Takahira M, Hamaoka S, Ikeda H, Gabata T, Kawano M. Mod Rheumatol. 2019 Mar;29(2):377-382.

2018年度

  1. Pulmonary carcinosarcoma showing an obvious response to pazopanib: a case report. Tanimoto A, Takeuchi S, Kotani H, Yamashita K, Yamada T, Ohtsubo K, Ebi H, Ikeda H, Yano S. BMC Pulm Med. 2018 Dec 12;18(1):193.
  2. Efficacy and Limitations of F-18-fluoro-2-deoxy-D-glucose Positron Emission Tomography to Differentiate Between Malignant and Benign Bone and Soft Tissue Tumors. Miwa S, Mochizuki T, Yamamoto N, Shirai T, Hayashi K, Takeuchi A, Inatani H, Igarashi K, Higuchi T, Abe K, Taniguchi Y, Aiba H, Ikeda H, Tsuchiya H. Anticancer Res. 2018 Jul;38(7):4065-4072.
  3. Imaging Somatostatin Receptor Activity in Neuroendocrine-differentiated Prostate Cancer. Mori H, Nakajima K, Kadomoto S, Mizokami A, Ikeda H, Wakabayashi H, Kinuya S. Intern Med. 2018 Nov 1;57(21):3123-3128.
  4. Peri-tumoral hyperintensity on hepatobiliary phase of gadoxetic acid-enhanced MRI in hepatocellular carcinomas: correlation with peri-tumoral hyperplasia and its pathological features. Yoneda N, Matsui O, Kitao A, Komori T, Kozaka K, Ikeda H, Yoshida K, Inoue D, Minami T, Koda W, Kobayashi S, Gabata T. Abdom Radiol (NY). 2018 Aug;43(8):2103-2112.
  5. Differentiation between phyllodes tumours and fibroadenomas using intravoxel incoherent motion magnetic resonance imaging: comparison with conventional diffusion-weighted imaging. Kawashima H, Miyati T, Ohno N, Ohno M, Inokuchi M, Ikeda H, Gabata T. Br J Radiol. 2018 Apr;91(1084):20170687.
  6. Gadoxetic acid-enhanced magnetic resonance imaging reflects co-activation of β-catenin and hepatocyte nuclear factor 4α in hepatocellular carcinoma. Kitao A, Matsui O, Yoneda N, Kozaka K, Kobayashi S, Koda W, Minami T, Inoue D, Yoshida K, Yamashita T, Yamashita T, Kaneko S, Takamura H, Ohta T, Ikeda H, Sato Y, Nakanuma Y, Harada K, Kita R, Gabata T. Hepatol Res. 2018 Feb;48(2):205-216.
  7. LatY136F knock-in mouse model for human IgG4-related disease. Yamada K, Zuka M, Ito K, Mizuguchi K, Kakuchi Y, Onoe T, Suzuki Y, Yamagishi M, Izui S, Malissen M, Malissen B, Kawano M. PLoS One. 2018 Jun 14;13(6):e0198417.
  8. Distribution and Morphological Features of Microglia in the Developing Cerebral Cortex of Gyrencephalic Mammals. Mizuguchi K, Horiike T, Matsumoto N, Ichikawa Y, Shinmyo Y, Kawasaki H. Neurochem Res. 2018 May;43(5):1075-1085.

学会発表

2022年度

  1. 第63回日本臨床細胞学会総会. 発表.  下田翼、水口敬司、嶋口智恵、酒野香織、森龍也、中田聡子、池田博子. 尿細胞診におけるフラクタル解析の有用性.
  2. 第61回日本臨床細胞学会秋期大会. 発表.  森龍也、水口敬司、嶋口智恵、酒野香織、下田翼、藤田一希、阪口真希、吉村かおり、中田聡子、池田博子. 胸水細胞診材料で転移を推定し得た尿路上皮癌の1例.

2021年度

  1. 第37回日本臨床細胞学会北陸連合会. 発表.  下田翼、水口敬司、嶋口智恵、酒野香織、森龍也、中田聡子、野島孝之、池田博子. 尿細胞診におけるフラクタル解析の有用性.
  2. 第60回日本臨床細胞学会秋期大会. ワークショップ.  水口敬司、嶋口智恵、酒野香織、下田翼、森龍也、阪口真希、吉村かおり、中田聡子、野島孝之、原田憲一、池田博子. 膵胆管領域のIgG4関連疾患における細胞診の可能性. 

2020年度

  1. 第61回日本臨床細胞学会春期大会. ポスター.  下田翼、水口敬司、嶋口智恵、玉野裕子、酒野香織、田中愛衣、中田聡子、野島孝之、池田博子. 胸水細胞診でCLL/SLLと肺腺癌の合併を診断しえた一例
  2. 第59回日本臨床細胞学会秋期大会. シンポジウム. 水口敬司. 嶋口智恵、酒野香織、下田翼、吉村かおり、阪口真希、野島孝之、中田聡子、池田博子. 胆管狭窄における炎症性疾患の細胞像. 

2019年度

  1. 第35回石川県臨床細胞学会学術集会、2019年、石川. 浅村倫孝、今度邦博、玉野裕子、酒野香織、宮下麻代、下田翼、藤田一希、池田博子、野島孝之. 原発性胆管癌と鑑別を要した乳癌胆管転移の一例
  2. 第60回日本臨床細胞学会総会(春期大会). 酒野香織、水口敬司、玉野裕子、宮下麻代、下田翼、阪口真希、池田博子、野島孝之、大井章史. 子宮腺肉腫の一例
  3. 第60回日本臨床細胞学会総会(春期大会).下田翼、水口敬司、玉野裕子、酒野香織、宮下麻代、阪口真希、池田博子、野島孝之、大井章史. CIC-rearranged sarcomaの細胞像の検討
  4. 第36回日本臨床細胞学会北陸連合会学術集会. 藤田一希、水口敬司、嶋口智恵、玉野裕子、酒野香織、下田翼、田中愛衣、中田聡子、野島孝之、池田博子. 膵神経内分泌腫瘍に置けるセルブロックを用いたKi-67 indexの正確性
  5. 第58回日本臨床細胞学会秋季大会. シンポジウム. 水口敬司,嶋口知恵,玉野裕子,酒野香織,下田翼,中田聡子,野島孝之,池田博子. 膵臓EUS-FNAにおける診断精度向上のための工夫
  6. 第58回日本臨床細胞学会秋季大会. ポスター. 玉野裕子,水口敬司,嶋口智恵,酒野香織,下田翼,田中愛衣,阪口真希,中田聡子,野島孝之,池田博子. ROS1融合遺伝子陽性肺癌の細胞像
  7. Kengo Saito, Keishi Mizuguchi, Toshihide Horiike, Tung Anh Dinh Duong, Yohei Shinmyo and Hiroshi Kawasaki. Uncovering the features of fiber layers in the developing cerebral cortex of mice and ferrets. New Frontier in Neuroscience 2019

2018年度

  1. 第107回日本病理学会総会. 阪口真希, 池田博子, 吉村かおり, 横山理菜, 野島孝之, 大井章史. 脳室内神経鞘腫の1例
  2. 第36回日本脳腫瘍病理学会. 阪口真希, 木下雅史, 宮下勝吉, 田中慎吾, 池田博子, 野島孝之, 中田光俊. 頭蓋内原発横紋筋肉腫の一例
  3. 第82回日本病理学会中部支部交見会. 吉村かおり、池田博子、横山理菜、阪口真希、野島孝之、大井章史. FISHが診断に有用であった腹膜結節の1例
  4. 玉野裕子、今度邦博、酒野香織、宮下麻代、下田翼、池田博子、大井章史. 胆膵領域におけるOn site cytology検体の肉眼所見と細胞像. 第59回日本臨床細胞学会総会、2018年、北海道
  5. 酒野香織、今度邦博、玉野裕子、田口憲子、宮下麻代、下田翼、池田博子、大井章史. 非定型奇形腫様ラブドイド腫瘍の1例. 第59回日本臨床細胞学会総会、2018年、北海道
  6. 下田翼、今度邦博、玉野裕子、酒野香織、宮下麻代、池田博子、野島孝之、大井章史. タモキシフェンによる子宮内膜細胞診への影響. 第35回日本臨床細胞学会北陸連合学術集会、2018年、福井
  7. 宮下麻代、今度邦博、玉野裕子、酒野香織、下田翼、池田博子、野島孝之、大井章史. 頸部軟部発生のEwing肉腫/PNETの細胞像の検討第37回日本臨床細胞学会秋季大会、2018年、神奈川
  8. Waseda Y, Matsui S, Yamada K, Mizuguchi K, Watanabe S, Ito K, Zuka M, Malissen M, Malissen B, Kawano M, Ishizuka T. Evalution of lung lesion in LATY136F mutant mice. American journal of respiratory and critical care medicine 2018; 197: A3020.

研究費

2020年度

  • 中田聡子:令和元年 科学研究費補助金 若手研究
    「再発・悪性髄膜腫におけるVEGFR-2のシグナル伝達経路の解明」
  • 水口敬司:令和元年 科学研究費補助金 若手研究
    高等哺乳動物を用いた胎児脳回形成異常に関与するシグナル経路の解明」

受賞

2019年度

  • 下田 翼:日本臨床細胞学会北陸連合会 谷本賞 (学術奨励賞)